(KO Validated) CD68 Polyclonal Antibody, Rabbit

Abbreviation: CD68

Target Synonym: CD68;GP110;LAMP4;SCARD1

Conjugation: Unconjugated

UNIProt ID: P34810

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD68

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93358-120
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93358-120
• Green Labware: No
• Package Unit: 120 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit