Abbreviation: SUMO1
Target Synonym: SUMO1; DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1; small ubiquitin-like modifier 1
Conjugation: Unconjugated
UNIProt ID: P63165
Background: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human SUMO1
Dilution: WB 1:500-1:2000,IHC 1:50-1:100,IF 1:50-1:200