Clone Name: H-6
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 70
Positive Control: Tonsil
Form: Liquid
Buffer (with preservative): PBS, 0.1% BSA, 0.05% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Uniprot ID: P12956
Antigen Species: Human
Immunogen: Ku-(p70) is a mouse monoclonal antibody specific for an epitope mapping between amino acids 583-608 at the C-terminus of KU70 of human origin.
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: X-ray repair cross complementing 6
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