Clone Name: MT155
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 21
Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-23 and recognizes the p19 subunit of the IL-23 heterodimer (p40 + p19). In combination with MT86/221, it detects IL-23 heterodimer (p40 + p19) by sandwich ELISA.
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9NPF7
Antigen Species: Human
Immunogen: Recombinant human IL-23
Purification: Protein G purified
Conjugation: Biotin
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