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Encompassing Amino Acids: 23-450
Application: Useful for studying protein binding and screening small molecular inhibitors
Description: Human secreted LAG3, also known as Lymphocyte-Activation Gene 3 and CD223. GenBank Accession No. NM 002286, a.a. 23-450 expressed in a HEK293 cell expression system with C-terminal His-Tag. MW = 48 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 20 mM NaOAC, pH 5.5, 500 mM NaCl, 0.02% Tween 20 and 10% glycerol.
Genbank: NM_002286
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: C-terminal His-Tag
Uniprot: P18627
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Byrnes, et al. Cytometry A. 2012 Sep;81(2):165-8.
2. Di, Carlo., et al., J. Pathol. 2005 Jan; 205(1):82-91.
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