Formulation: A powder
Formal Name: 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl-9H-pyrido[3,4-b]indole-3-carboxylic acid
Purity: ≥90%
Formula Markup: C22H14N4O4
Formula Weight: 398,4
Shelf life (days): 1460
CAS Number: 81645-09-2
Notes: Lavendamycin is a bacterial metabolite that has been found in S. lavendulae and has antimicrobial and anticancer activities.{72551,72552} It is active against various bacteria, including S. pneumoniae, S. aureus, E. coli, P. mirabilis, and P. vulgaris (MICs = 0.13-1 µg/ml), and various fungi, including T. rubrum, T. mentagrophytes, and M. canis (MICs = 0.5 µg/ml for all).{72551} Lavendamycin is cytotoxic to P388 murine leukemia, MKN45 gastric carcinoma, and WiDr colon adenocarcinoma cells (IC50s = 0.06, 0.1, 0.09 µg/ml, respectively).{72552} In vivo, lavendamycin (0.4-6.4 mg/kg) increases median survival time in a P388 murine leukemia model.{72551}
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