Lead-like Diverse Library Plus

Advantages:

Compounds in this library with a high divesity and broad chemical space coverage.
• Compounds in this library with a high divesity and broad chemical space coverage.
• Compatible with “Lipinski’s Rule of Five”, with multiple characteristics such as calculated good permeability (-3.2 < logP < 5), oral bioavailability (RotB <= 10), drug transportability (PSA < 120), MW between 300 to 500, number of Hydrogen Bond Donor (HBD) ≤ 5, number of Hydrogen Bond Acceptor (HBA) ≤ 10.
• Passed all associated MedChem filters, particularly pan assay interference compound (PAINS) motifs, to remove any inappropriate chemical structures and avoid false hits.
• All compounds are available off the shelf. Pre-plates of 10 mM DMSO solutions, convenient to use.
• LCMS or NMR validated to ensure high purity and quality.

Formulation: Consisting of over 80,000 lead-like compounds with 50,000 scaffolds (Bemis-Murcko).

Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know.

Container: 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

• SKU: MEXHY-L901P-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-L901P-50
• Package Unit: 50 µl
• Quantity Unit: STK