LH 846, CAS 639052-78-1

Casein kinase 1d inhibitor

Product Type: Inhibitor

CAS No.: 639052-78-1

MolecularFormula: C16H13ClN2OS

Molecular Weight: 316,8

Source: Synthetic

Purity: ≥98% (HPLC)

Solubility: Soluble to 100 mM in DMSO

Appearance: White to beige powder

PubChem CID: 851474

Scientific Background: LH 846 is a potent and selective inhibitor of Casein Kinase CK1δ. Specifically, it inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. CK1δ is a known regulator of circadian rhythm.

References: 1. Lee J.W., et al. (2011) Angewandte Chemie. 50(45): 10608–10611.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-503-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-503-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK