Lipid 10, CAS 2430034-02-7

Formulation: A solution in methyl acetate

Formal Name: 4-methyl-1-piperazinepropanoic acid, 2-[di-(9Z,12Z)-9,12-octadecadien-1-ylamino]ethyl ester

Purity: ≥95%

Formula Markup: C46H85N3O2

Formula Weight: 712,2

Shelf life (days): 365

CAS Number: 2430034-02-7

Notes: Lipid 10 is an ionizable cationic lipid (pKa = 6.2-6.5).{55517} Lipid nanoparticles (LNPs) containing lipid 10 and encapsulating siRNA for the gene encoding cytoskeleton-associated protein 5 (CKAP5) reduce its gene expression and protein levels in vitro and selectively reduce cell viability in a variety of genetically unstable cancer cell lines.{66475} Administration of LNPs containing lipid 10 and encapsulating CKAP5 siRNA reduce tumor growth and increase survival in an NCI/ADR-RES human ovarian cancer mouse xenograft model.

• SKU: CAY38705-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38705-10
• Package Unit: 10 mg
• Quantity Unit: STK