Abbreviation: LLGL2
Target Synonym: HGL;Hugl-2;LGL2;LLGL2
Conjugation: Unconjugated
UNIProt ID: Q6P1M3
Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human LLGL2
Dilution: WB 1:500-1:2000