Abbreviation: LPXN
Target Synonym: LPXN;LDPL;leupaxin
Conjugation: Unconjugated
UNIProt ID: O60711
Background: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human LPXN
Dilution: WB 1:500-1:2000
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