Application Note: WB: 1:2000 - 1:5000. ICC/IF: 1:1000 - 1:2000. IHC-P: 1:500 - 1:1000. FACS: 1:200. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 286
Form: Liquid
Buffer (with preservative): Tris-Citrate/Phosphate, 0.1% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq]
Uniprot ID: Q5S007
Antigen Species: Human
Immunogen: A C-terminal synthetic peptide made to the human LRRK2 protein sequence (between residues 2500-2527). [UniProt# Q5S007]
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: leucine rich repeat kinase 2
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