Application Note: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 286
Positive Control: IMR32 , mouse cerebellum
Form: Liquid
Buffer (with preservative): 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq]
Uniprot ID: Q5S007
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the center region of human LRRK2. The exact sequence is proprietary.
Purification: Purified by antigen-affinity chromatography.
Conjugation: Unconjugated
Full Name: leucine rich repeat kinase 2
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