Product Description: MA-PEG4-VC-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using the DNA minor-groove alkylator Duocarmycin DM (HY-130978), linked via MA-PEG4-vc-PAB-DMEA (HY-126668).
Applications: Cancer-programmed cell death
Formula: C68H89ClN12O17
References: [1]Patil PC, et al. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents. Anticancer Agents Med Chem. 2015;15(5):616-30./[2]Italo Beria, et al. New alkylating agents. Franch, WO2013149948A1.
Molecular Weight: 1381.96
Compound Purity: 99.84
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC