Product Description: Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan is a Drug-Linker Conjugates for ADC, which comprises a topoisomerase inhibitor and a linker for ligand unit connecting. Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan can be used to synthesis antibody-drug conjugate (ADC)[1].
Applications: Cancer-programmed cell death
Formula: C57H77N7O18
References: [1]Philip Wilson Howard, et al. Compounds and conjugates thereof. Patent US20200306243A1./[2]Schmidt, et al. Computer-based scoring method indicating a cancer patient's response to an anti-B7H4 antibody-drug conjugate therapy using a convolutional neural network, WO2022053685, 2022.
CAS Number: 2495742-34-0
Molecular Weight: 1148.26
Compound Purity: 98.95
Research Area: Cancer
Solubility: DMSO : 200 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Drug-Linker Conjugates for ADC;Topoisomerase