Formulation: A solution in methanol
Formal Name: 1,4-diethyl 2-[[di(methoxy-d3)phosphinothioyl]thio]butanedioate
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C10H13D6O6PS2
Formula Weight: 336,4
Shelf life (days): 730
CAS Number: 1189877-72-2
Notes: Malathion-d6 is intended for use as an internal standard for the quantification of malathion (Item No. 22998) by GC- or LC-MS. Malathion is an organophosphate insecticide that inhibits acetylcholinesterase (AChE; IC50s = 370 and 160 µM for free and immobilized AChE, respectively, from bovine erythrocytes).{37737} It is ovicidal and adulticidal to laboratory colonies of body lice when used at concentrations of 0.001 and 0.05%, respectively.{37738} It is toxic to rats (LD50 = 750 mg/kg) and teratogenic to zebrafish when used at concentrations ranging from 2 to 3 mg/L.{37739,37740} Formulations containing malathion have been used in the treatment of lice.