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Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: Methionine Adenosyltransferase 2A (MAT2A), also known as AdoMet Synthase 2, catalyzes the formation of S-adenosylmethionine from methionine and ATP. It is an important enzyme in cellular metabolism and is expressed in extrahepatic tissues. In liver, MAT2a expression is associated with growth, dedifferentiation, and cancer.
Description: The MAT2a Inhibitor Screening Assay Kit is designed to measure MAT2A activity for screening and profiling applications. The MAT2A assay kit comes in a convenient 384-well format, with purified recombinant MAT2A enzyme, L-Methionine, ATP, MAT2A assay buffer, and Colorimetric detection reagent for 384 enzyme reactions.
Storage Stability: Up to 6 months from date of receipt, when stored as recommended.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Frau, M., et al., Hepatology, 56 (1), 165-175 (2012)
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