Product Description: MC-vc-PAB-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker)[1].
Applications: Cancer-programmed cell death
Formula: C66H93N11O15S
References: [1]Wang Y, et al. Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules. Mol Pharmacol. 2016 Feb;89(2):233-42.
CAS Number: 1639939-56-2
Molecular Weight: 1312.57
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC;Microtubule/Tubulin