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Encompassing Amino Acids: 2-327
Applications: Useful for the study of apoptosis, screening inhibitors, and selectivity profiling.
Description: Human MCL1, also known as Induced myeloid leukemia cell differentiation protein and BCL2L3, GenBank Accession No. NM_021960, a.a. 2-327, with N-terminal His-tag, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 3mM DTT, 20% glycerol, additional 200mM Imidazole
Genbank: NM_021960
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 - 0.5%).
Tags: N-terminal His-tag
Uniprot: Q07820
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Kozopas, K., et al., PNAS. 1993; 90(8): 3516-3520.2. Leu, T., et al., New England Journal of Medicine. 2013; 368: 107-116.