Abbreviation: MCOLN2
Target Synonym: TRP-ML2;TRPML2;MCOLN2
Conjugation: Unconjugated
UNIProt ID: Q8IZK6
Background: Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009]
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MCOLN2
Dilution: WB 1:500-1:2000