Clone Name: YP158
Application Note: IHC-P: 1:10-1:15. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 69
Positive Control: Mesothelioma
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Uniprot ID: Q13421
Antigen Species: Human
Immunogen: Synthetic peptide corresponding to c-terminus of human mesothelin protein
Purification: Unpurified
Conjugation: Unconjugated
Full Name: mesothelin
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