Formulation: A solid
Formal Name: L-tyrosylglycylglycyl-L-phenylalanyl-L-methioninamide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C27H36N6O6S • XCF3COOH
Formula Weight: 572,7
Shelf life (days): 1460
Notes: Met-Enkephalinamide is a peptide opioid receptor agonist and derivative of Met-enkephalin (Item No. 23284).{62706,62707} It binds to opioid receptors in rat cerebellum homogenates (IC50 = 0.2 µM) and reduces the twitch height in electrically stimulated isolated guinea pig ileum and isolated mouse vas deferens. Met-Enkephalinamide (300 µg/animal) induces analgesia in the hot plate and tail-flick tests in rats, effects that can be reversed by administration of the opioid receptor antagonist naloxone.{62708}