Formulation: A solid
Formal Name: 2-chloro-6-(1-piperazinyl)-pyrazine, monohydrochloride
Purity: ≥98%
Formula Markup: C8H11ClN4 • HCl
Formula Weight: 235,1
Shelf life (days): 1460
CAS Number: 61655-58-1
Notes: MK-212 is an agonist of the serotonin (5-HT) receptor subtype 5-HT2C (EC50 = 0.028 µM in a calcium mobilization assay).{58910} It is selective for 5-HT2C over 5-HT2A receptors (EC50 = 0.42 µM). MK-212 reduces food intake in fasted rats with an ED50 value of 5 mg/kg.{58911} It reduces cocaine-primed reinstatement of cocaine-seeking behavior in rats when administered at doses of 0.32, 0.56, or 1 mg/kg.{58912}