Product Description: ML345 is a potent and selective insulin-degrading enzyme (IDE) small-molecule inhibitor, with an IC50 value of 188 nM. ML345 can be for use as a pharmacophore for agent development in diabetes research[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C21H22FN3O5S2
References: [1]Bannister TD, et al. ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE). In: Probe Reports from the NIH Molecular Libraries Program. Bethesda (MD): National Center for Biotechnology Information (US); December 17, 2012.
CAS Number: 1632125-79-1
Molecular Weight: 479.54
Compound Purity: 98.30
Research Area: Metabolic Disease
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: Proteolytic Enzyme