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Applications: Great for studying enzyme kinetics and HTS applications.
Background: MMP1 (matrix metalloproteinase 1) is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix. MMP1 is also associated with the regulation of cytokines and chemokines, suggesting a role for MMP1 in inflammation.
Description: The Fluorogenic MMP1 Assay Kit is designed to measure MMP1 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
Storage Stability: One year from date of receipt when stored as directed.
Supplied As: The kit comes in a convenient 96-well format, with purified MMP1 enzyme, fluorogenic substrate, and MMP1 assay buffer for 100 enzyme reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Foley, C.J., and Kuliopulos, A. Mouse Matrix metalloprotease-1a (Mmp1a) Gives New Insight Into MMP Function. J. Cell Physiol. 2014 Dec; 229(12):1875-80.
2. Pardo, A., and Selman, M. MMP-1: The Elder of the Family. Int. J. Biochem. Cell Biol. 2005 Feb; 37(2):283-8.