Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MMP26
Molecular Weight: 19kDa
Peptide Sequence: Synthetic peptide located within the following region:
NLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Matrix metalloproteinase-26
Protein Size: 261
Purification: Affinity Purified
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