Clone Number: 3-3A
Immunogen: mixture of erythrocytes of blood group A1 and a glycoprotein fraction isolated from the salvia of secretors with blood group A of human origin
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: 3-3A reacts with determinants of chain A type 3 and 4 and chain H type 3 and 4, but not with type 1 and 2 chain structures. It is not reactive with immunodominant A trisaccharide. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas. 3-3A does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues in these individuals.
References: Bara, J. et al. Biochem. J. 254: 185-193 (1988)/Yasumsds, I. et al. Glycoconjugate J. 3: 187-202 (2000)/Rouger et al. Blood transfusion and immunohematol. 30(5): 252-720 (1987)
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