Clone Number: MMA
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: CD15 is a carbohydrate antigen with the common trisaccharide structure 3-fucosyl-N-acetyllactosamine, also known as Lewis x (Lex) or stage-specific embryonic antigen 1 (SSEA-1).1-3 CD15 is expressed in myeloid cells and mediates neutrophil adhesion to dendritic cells.2-3 CD15 is also expressed in Reed-Sternberg cells and is thus a useful marker for identifying Hodgkin’s lymphoma.
References: Pellegrini W, et al. Haematologica. 2007; 92:708-9/Stocks SC, et al. Biochem J. 1990; 268: 275–80/Gadhoum SZ, et al. Nat Chem Biol. 2008; 4:751-7