Clone Number: EBS-CD-013
Immunogen: BLs from a NK-leukemia patient
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBS-CD-013 specifically recognizes CD16. This molecule also named low affinity Fc-receptor for IgG (FcgammaRIII) exhibits two truncated Ig-like domains and is 50-80 kDa. It is highly expressed on NK-cells, granulocytes and macrophages. EBS-CD-013 binds to 15% peripheral lymphocytes of healthy donors (NK-cells), granulocytes, macrophages. CD16 represents the functional receptor structure for antibody-dependent cellular cytotoxicity.
References: Deaglio S. et al., Blood 99(7): 2490-8 (2002)/Zilber MT et al. Proc Natl Acad Sci U S A 97(6): 2840-5 (2000)/Wirthmueller U et al. J Exp Med. 175(5): 1381-90 (1992)