Clone Number: BT51E
Immunogen: A prokaryotic fusion protein containing part of the C-terminal region of the human CD19 molecule.
Concentration: Greater than or equal to 35 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein present on the surface of B lymphocytes and follicular dendritic cells of the hematopoietic system. CD19 is a crucial regulator in B cell development, activation and differentiation. On B cells, CD19 associates with CD21, CD81 and CD225 (Leu-13) forming a signal transduction complex. CD19 is expressed from the earliest recognizable B cell lineage stage, through development to B cell differentiation but is lost on maturation to plasma cells.
References: Fujimoto M and Sato S. Journal of Dermatological Science. 2007; 46:1-9/Otero D et al. The Journal of Immunology. 2003; 170: 73-83/Fujimoto M et al. Seminars in Immunology. 1998; 10:267-277
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