Mouse anti-CD22, clone FR10B4 (Monoclonal)

Clone Number: FR10B4

Immunogen: RAJI cells

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: FR10B4 reacts with high affinity to CD22, which is expressed in the cytoplasma of all B-cells, appearing as early as cell-surface CD19 during B-cell development. It’s present on the surface of most mature sIg+ B-cells with especially high expression on hairy cell and prolymphocytic leukemia cells. CD22 is a member of the immunoglobulin super-family and acts as an adhesion molecule: BL-CAM. On frozen sections, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, while germinal centre B-cells react relatively weakly.

References: Campana, D., et al.Leucocyte Typing IV, Oxford Univ. Press, (1989), pp 190-192

• SKU: SANMON9933
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9933
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotype: IgG1-k
• Host: Mouse
• Conjugate: Unconjugated