Clone Number: 4C9
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: CD25, Interleukin-2 receptor alpha chain, is the alpha subunit of the cell surface receptor which regulates regulatory T-cells. CD25 has been detected in various hematological malignancies including adult T-cell leukemia/lymphoma, and hairy cell leukemia. MON 3230 has also been useful in identifying mast cells in skin biopsies in the setting of Urticaria Pigmentosa, which is predictive of Systemic Mastocytosis.
References: Hahn HP, et al. Am J Surg Pathol. 2007 Nov;31(11):1669-76/Hollmann TJ, et al. Am J Surg Pathol. 2008 Jan;32(1):139-45/Létourneau S, et al. Clin Immunol. 2009; 123:758-62