Clone Number: Ber-H2
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: The antibody detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classicHodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positiveT-cell lymphoproliferative disorders and in embryonal carcinomas. Occasionally diffuse large B-celllymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissueas well as reactive immunoblasts. The staining pattern of anti-CD30 in lymphoma and embryonalcarcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation inlocation, and the latter being membranous only.
References: Schwarting R, et al., Blood 1989 (74):1678-1689/Fonatsch C, et al., Genomics 1992 (14):825-826/George DH et al. Am J Surg Pathol. 2003 Apr;27(4): 487-93
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