Clone Number: MX032
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Format: Concentrate
Storage buffer: Tissue culture supernatant containing 15mM sodium azide.
Additional info: CD31 is a transmembrane glycoprotein, 130-140 kDa, also designated platelet-endothelium cell adhesion molecule = PECAM-1, belonging to the immunoglobulin super family. CD31 is ligand for CD38 and plays a role in thrombosis and angiogenesis. CD31 is strongly expressed in endothelial cells and weakly expressed in megakaryocytes, platelets, occasional plasma cells, lymphocytes (esp. marginal zone B-cells, peripheral T-cells) and neutrophils. Pre-treatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH6.0 for 20 minutes is required for IHC staining on formalin-fixed, paraffin embedded tissue sections. Note: Dilution of the antibody in 10% normal goat serum followed by a goat anti-mouse secondary antibody-based detection is recommended. Control tissue Tonsil. Staining Membranous
References: Santonja C, Martin-Hita AM, Dotor A, et al., Virchows Arch 2001;438;404-7/Marquez WH, Gomez-Hoyos J, Woodcock S, et al., Hip Int 2015; 25:168-71