Clone Number: EDU-2
Immunogen: stimulated human leucocytes
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EDU-2 reacts with human CD4, a 55 kDa single chain transmembrane glycoprotein that contains four extracellular immunoglobulin-like domains and is mainly expressed on T-helper lymphocytes, but also on cortical thymus cells, microglial and dendritic cells. It binds to HLA class II molecules during the interaction of CD4+ T cells with antigen-presenting cells or target cells. CD4 also serves as the primary cellular receptor for human immunodeficiency virus (HIV). EDU-2 was assigned to CD4 at the International Leucocyte Typing Workshops II and IV.
References: Knapp W. Leukocyte Typing IV, Oxford Univ. Press, (1989)/Reinberz EL et al. eds. Leykcocyte Typing II, Springer-Verlag, Berlin, (1985)
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