Clone Number: 4C7
Immunogen: Recombinant prokaryotic fusion protein corresponding to the external domain of the human CD5 molecule.
Concentration: Greater than or equal to 76 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: CD5 antigen is reported to be expressed on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed on T cells. CD5 antigen is also expressed by many T cell leukemias, lymphomas, activated T cells and on a subset of B cells located primarily in the mantle zones of normal lymph nodes. CD5 antigen expression is also reported in T cell acute lymphocytic leukemias (T-ALL), some B cell chronic lymphocytic leukemias (B-CLL) as well as B and T cell lymphomas.
References: Leong FJW et al. The Journal of Histotechnology. 2002; 25(4):215-227/Walsh R et al. Arch. of Pathol.and Lab.Medicine. 2001; 125(6):781-784/Tateyama H et al. American Journal of Clinical Pathology. 1999; 111(2):235-240