Mouse anti-CD57, clone NK-1 (Monoclonal)

Clone Number: NK-1

Immunogen: preparation of HSB-2 T cell line

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: CD57, also known as HNK-1 (human natural killer-1), is a cell surface carbohydrate epitope expressed on terminally differentiated T-cells and subsets of natural killer (NK) cells.1 It has also been identified on cells of neural crest origin.2 Anti-CD57 is often used to visualize the non-neoplastic bystander T-cells that may form rosettes around the neoplastic lymphocyte-predominant (LP) cells in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL).3

References: Kared H, et al. Cancer Immunol Immunother. 2016; 65:441-52/Nielsen CM, et al. Front Immunol. 2013; 4:422/Sattarzadeh A, et al. Exp Hematol Oncol. 2015; 4:27

• SKU: SANMON1012P
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON1012P
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgM-k
• Host: Mouse
• Conjugate: Unconjugated