Clone Number: CB-30
Immunogen: human colon cancer extract
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: CB-30 reacts with CD66e or CEA with MW of 80-200 kDa. CEA is present in fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Ant-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.
References: Ashley N et. al. J Pathol. 234(1):34-45 (2014)