Clone Number: IPO-10
Immunogen: human B-cell line Daudi
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: CDw78 (also called Ba antigen, Leu21 or LO panB a) is present on some immature and some mature B-cells. The antigen appears on B-cell progenitors preceding CD10, CD19, CD22 and CD37. It is expressed on resting B-cells and reappears and persists in the cytoplasm and on the cell surface until cytoplasmic Ig appears. Its expression is greatly increased after B-cell activation in vitro. It is also found on tissue macrophages and on epithelial cells, but not on Tcells, NK-cells, monocytes, granulocytes, thymocytes or bone marrow stromal fibroblasts nor myeloid tissues.
References: Pinchouk V.G. et al, Anticancer Res. 8: 1377-1380 (1988)/Gluzman DF. et al, Tissue Antigens 33: 151 (1989)/Sidorenko SP. et al, Neoplasma 39: 3-9 (1992)
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