Mouse anti-CEA-2, clone 12-140-10 (monoclonal)

Clone Number: 12-140-10

Immunogen: CEA isolated from liver metastasis of colorectal carcinomas by PCA extraction followed by ion exchange and gel filtration chromatography.

Concentration: Greater than or equal to 38 mg/L

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: Carcinoembryonic antigen (CEA),(CD66e) is a heterogeneous cell surface glycoprotein produced by cells of fetal colon. Low levels are also found on normal mucosal epithelia of the adult colon and a variety of other normal tissues. CEA is encoded by the CEA gene, which is located on chromosome 19. It is a member of the CEA gene family, which in turn is a subfamily of the immunoglobulin superfamily. Cell adhesion properties are now well recognized for CEA. It is believed that the expression of this glycoprotein in conjunction with other known adhesion molecules will influence the cell-cell interaction.

References: Lee OJ and Lee HC. The Korean Journal of Pathology. 2010; 44: 666-669/Chung-Chin Y et al.Archives of Gynecology and Obstetrics 2009;208:3: 405-413/Gimelli S et al. Molecular Cancer 2009;8: 52-65

• SKU: SANMONX11148
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MONX11148
• Package Unit: 1ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated