Clone Number: EBP-333
Immunogen: human C/EBPb recombinant protein
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBP-333 reacts with C/EBPβ or CCAAAT/enhancer-binding protein beta, a transcription factor which is not only critical for normal macrophage functioning and differentiation, but affects a variety of other factors as well, such as cytokines (IL-6; IL-4; IL-5 and TNF-alpha), neurotransmitters and other neuronal factors and processes like muscle repair and the development of multi drug resistance in tumors (P-glycoprotein). Observations have implied that manipulation of the transcription factors involved may make it possible to modulate multidrug resistance, while leaving normal function of P-glycoprotein intact.
References: Couturier, C et al, Arterioscler Thromb Vasc Biol. 20(12): 2559-65 (2000)/Qin, L et al, Biomaterials 59: 125-43 (2015)
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