Clone Number: 13B10
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Human herpesvirus type 8 (HHV-8) is the likely etiological agent of Kaposi’s sarcoma (KS). HHV-8 DNA sequences have been found in Kaposi’s sarcoma lesions, primary effusion lymphoma, and multicentric Castleman’s disease via polymerase chain reaction and in situ hybridization. Latent nuclear antigen (LNA1, LNA, LANA-1), also known as ORF73, is a 222- or 234 kD protein that is consistently expressed in HHV8 infected cells. Anti-HHV-8 labels the latent nuclear antigen protein via immunohistochemistry
References: Corbellino M et al AIDS Res Hum Retroviruses.;12(8):651-7 (1996)/Schwartz EJ et al. Am J Surg Pathol.;27(12):1546-50 (2003)/Boulanger E et al. Am J Hematol.;76(1):88-91 (2004)
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