Clone Number: 7.5.10.1
Immunogen: Human EVB-transformed B-cell line DR3/3
Concentration: n/a
Storage buffer: PBS with 0.1% BSA and 0.02% sodium azide
Additional info: The antibody reacts with a monomorphic determinant on MHC class II, HLA-D region molecules. It detects the molecules of the HLA-DR, DP and DQ loci. It inhibits the mixed lymphocyte culture. It also reacts with MHC class II molecules of various animals and is a useful tool for studies with dogs. The antibody is useful for the identification of HLA-D positive molecules using either microcytotoxicity testing or immunofluorescence/immunoperoxidase procedures. Furthermore, it was found useful for studies on functional aspects of MHC class II molecules.
References: Koning, F., et al., 1984, Human Immunology 9, 221/Koning, F., et al., 1985, Tissue Antigens 26, 100/Doveren, R.F., et al., 1986, Tissue Antigen 27, 87-98
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