Clone: 2H12.
Background: The immunogen for the anti-human bcl-xl was a synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence. Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. The ratio of bcl-xl to other family members is believed to modulate the apoptotic process.
Positive Control: Human, mouse and rat thymocytes.
Immunogen: A synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence.
Purification Method: Protein A/G Chromatography.
Formulation: Provided as solution in phosphate buffered saline with no preservative or carrier protein added.
References: 1) L.H. Boise, et. al. (1993) Cell, 74:597-608.
2) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834
3) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672.
UniProt: Q07817.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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