Clone: 2H12
Background: Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. The ratio of bcl-xl to other family members is believed to modulate the apoptotic process.
Positive Control: Human, mouse and rat thymocytes
Immunogen: A synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Source: Mice were immunized with a synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence.
References: 1) L.H. Boise, et. al. (1993) Cell, 74:597-608. 2) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834 3) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672
UniProt: Q07817
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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