Clone Number: DFT-1
Immunogen: KG-1 cells
Concentration: IgG 1 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human CD43 antibody, clone DFT-1 recognizes human CD43 also known as leukosialin or sialophorin. CD43 is a 381 amino acid single pass type I transmembrane glycoprotein present on the cell surface of multiple cell types including thymocytes, T-lymphocytes, neutrophils, plasma cells and platelets. It is lacking on the surface of most B-lymphocytes. CD34 is a major membrane sialoglycoprotein expressed on T lymphocytes as two predominant glycoforms, a ~115 kDa form present on all T-cells and a ~130 kDa form indicative of T-cell activation (Barren et al. 1997) and acts as a T-cell counter-receptor for CD169/Siglec-1 (van den Berg et al. 2001). Mouse anti Human CD43 antibody, clone DFT-1 binds to both glycoforms of human CD43 (Kyoizumi et al. 2004)
References: Stross WP et al. J Clin Pathol 1989; 42: 953-61/Kojima N et al. Exp Cell Res 1994; 214: 537-42/Anzai N et al. Blood 1999; 93: 3317-26
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