Clone Number: HM57
Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Concentration: IgG 1 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human CD79a antibody, clone HM57 recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signaling following antigen-binding to surface immunoglobulin.
References: Mason DY et al. J Immunol 1991; 147: 2474-82/Spaas JH Vet J 2013; 195: 107-13/De Schauwer C et al. Stem Cell Res Ther 2014; 5: 6