Mouse anti Human p130

Mouse anti Human p130, Monoclonal, IgG1, Clone: KAB40

Clone: KAB40

Background: P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa.

Positive Control: This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. And is suitable for use in western blot with his- tagged or GST tagged proteins.

Purification Method: Protein A/G Chromatography

Concentration: See vial for concentration

Source: The immunogen used was a recombinant protein to the N terminus of p130.

UniProt: Q08999 (Human)Q64700 (Mouse)O55081 (Rat)

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• SKU: EXAN105M
• Manufacturer: Exalpha Biologicals Inc
• Manufacturer SKU: N105M
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Western Blotting
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated