Clone: DCS-100
Background: The immunogen for the anti-h-p19 was a his-tagged recombinant full length p19 protein recognizing a 19kD protein. The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.
Immunogen: A his-tagged recombinant full length p19 protein recognizing a 19kD protein
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
References: 1) H. Hirai, et. al. (1995) Mol. Cell. Biol. (15) 2672-26812) JIRINA BARTKOVA, MINNA THULLBERG, PREMYSL SLEZAK, EDGAR JARAMILLO, CARLOS RUBIO, LARS H. THOMASSEN, and JIRI BARTEK. Aberrant Expression of G1-Phase Cell Cycle Regulators in Flat and Exophytic Adenomas of the Human Colon. GASTROENTEROLOGY 2001;120:1680–1688
UniProt: P55273 (Human)
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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