Clone Number: 8003 (99/12)
Immunogen: Purified human pepsinogen 1
Concentration: IgG 0.5 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human pepsinogen 1 antibody, clone 8003 recognizes human Pepsinogen I, a zymogen or proenzyme secreted by chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin). Mouse anti Human pepsinogen 1 antibody, clone 8003 has an affinity of 4 x 1010 l/molhuman Pepsinogen I.
References: Ueyama H et al. Am J Surg Pathol 2010; 34: 609-19/Fujita Y et al. Gastric Cancer 2016; 19: 192-7/Hidaka Y et al. Human Pathol 2013; 44: 2438-48