Clone Number: 97H6
Immunogen: his-tagged polypeptide containing residues 489–911 of mouse talin1
Concentration: IgG 1 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human Talin-1 antibody, clone 97H6 recognizes an epitope within the region of amino acids 482-655 of humanTalin-1, a high molecular weight cytoskeletal protein, linking vinculin to the integrins, thereby linking the cytoskeleton to the extracellular matrix. It is specifically found in regions of cell-substratum contact and in lymphocytes at cell-cell contact points. Talin-1 plays a role in the assembly of actin filaments and in the migration of cells such as osteoclasts and fibroblasts
References: Kopp PM et al. Eur J Cell Biol 2010; 89: 661-73/Manso AM et al. J Biol Chem 2013; 288: 4252-64/Liu J et al. Mol Cell Biol 2011; 31: 3366-77
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